LNX1 Antilichaam - C-terminal regio : HRP (ARP43367 T100-HRP)

Ligand of numb-protein X 1, E3 ubiquitin protein ligase

LNX, MPDZ, PDZRN2

84708

Q8TBB1-2

NP_116011

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit

The immunogen is a synthetic peptide directed towards the C terminal region of human LNX1

LNX1 is a membrane-bound protein that is involved in signal transduction and protein interactions. LNX1 is an E3 ubiquitin-protein ligase, which mediates ubiquitination and subsequent proteasomal degradation of proteins containing phosphotyrosine binding (PTB) domains. This protein may play an important role in tumorogenesis.This gene encodes a membrane-bound protein that is involved in signal transduction and protein interactions. The encoded product is an E3 ubiquitin-protein ligase, which mediates ubiquitination and subsequent proteasomal degradation of proteins containing phosphotyrosine binding (PTB) domains. This protein may play an important role in tumorogenesis. Alternatively spliced transcript variants encoding distinct isoforms have been described. A pseudogene, which is located on chromosome 17, has been identified for this gene.

GRB2; TRIP13; ZCCHC10; ROPN1; NECAB2; PRR13; ZNF581; APIP; MEMO1; ZNF593; OSGIN1; NME7; OSBP2; DNPEP; ISCU; MTUS2; RUVBL2; NEK6; RFPL3; AIDA; GDI1; ROBO3; PBLD; LSM2; HOMEZ; TRIM54; AGTRAP; LGALS14; TRIM39; NXT2; ZFP64; POMGNT1; GOLPH3L; TRMT12; FAM118A

HRP: Horseradish Peroxidase

Polyclonal Antibody

WB

0.5 mg/ml

Cow: 100%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

70kDa

Weiss, A., (2007) FEBS Lett. 581 (26), 5131-5136

Wet Ice

632

LNX1

LNX1

Rabbit

E3 ubiquitin-protein ligase LNX

NM_032622

SHREWDLPIYVISVEPGGVISRDGRIKTGDILLNVDGVELTEVSRSEAVA