LONP2 Antilichaam

In human, peroxisomes function primarily to catalyze fatty acid beta-oxidation and, as a by-product, produce hydrogen peroxide and superoxide. The protein encoded by this gene is an ATP-dependent protease that likely plays a role in maintaining overall peroxisome homeostasis as well as proteolytically degrading peroxisomal proteins damaged by oxidation. The protein has an N-terminal Lon N substrate recognition domain, an ATPase domain, a proteolytic domain, and, in some isoforms, a C-terminal peroxisome targeting sequence. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

83752

Q86WA8

Human, Mouse, Rat

Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human LONP2 (NP_113678.2) .

Unconjugated

Primary Antibodies

Cell Cycle

Affinity purification

U-87MG

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 110kDa

IgG

WB: 1:500 - 1:2000

LONP2

HeLa

A-375

Mouse kidney

Mouse liver

Mouse lung

Lon protease homolog 2, peroxisomal {ECO:0000255|HAMAP-Rule:MF_03121}

Homo sapiens

Lon protease homolog 2, peroxisomal {ECO:0000255|HAMAP-Rule:MF_03121}, 3421- {ECO:0000255|HAMAP-Rule:MF_03121}, Lon protease-like protein 2 {ECO:0000255|HAMAP-Rule:MF_03121}, Lon protease 2 {ECO:0000255|HAMAP-Rule:MF_03121}, Peroxisomal Lon protease {ECO:0000255|HAMAP-Rule:MF_03121}, LONP2 {ECO:0000255|HAMAP-Rule:MF_03121}, LONP

WB

Liquid