LPAM-1 Antilichaam [DATK32] (Biotine)

The lymphocyte Peyer’s patch adhesion molecule (LPAM-1), also known as integrin alpha4beta7, is a member of the integrin family of cell surface receptors. It is expressed primarily on mucosal lymphocytes but is also present on NK cells and eosinophils. The alpha4beta7 heterodimer mediates the binding of lymphocytes to its ligand, mucosal vascular addressin (MAdCAM-1) on the high endothelial venules, thereby directing the homing of lymphocytes into Peyer’s patches and intestinal lamina propria. The monoclonal antibody DATK32 recognizes a conformational epitope on the heterodimer.

16401;16421

Q00651; P26011

Q00651; P26011

Mouse

AKR/Cum mouse T lymphoma cell line TK-1

[DATK32]

Biotin

Primary Antibodies

Immunology, Signal Transduction, Stem Cell

0.5 mg/mL

Supplied in PBS/NaN3

None

Blue Ice

Store vial at 2-8˚ C

IgG2a

LPAM-1

LPAM-1 Antibody [DATK32] for use in flow cytometry, immunohistochemistry, and immunoprecipitation assays.

Itga4; Itgb7

Integrin alpha 4; integrin beta 7

Mus musculus

Integrin alpha4beta7, lymphocyte Peyer's patch adhesion molecule

ICC, Flow, IP

Liquid