LRP6-eiwit (C-His-AVI, menselijk)

LRP6

ADCAD2, STHAG7

C-His-AVI

< 1.0 EU per μg protein as determined by the LAL method.

≥ 90 % as determined by SDS-PAGE.

1.Loaded Recombinant Human LRP-6 Protein, His & AVI Tag, Avi-tag Biotinylated (Cat. No. 11968-H49H-B) on SA Biosensor, can bind Recombinant Human DKK-1 Protein, His Tag (Cat. No. 10170-H08H) with an affinity constant of 90.6 nM as determined in BLI assay (Sartorius Octet RED384) (Routinely tested) . 2.Loaded Recombinant Human LRP-6 Protein, His & AVI Tag, Avi-tag Biotinylated (Cat. No. 11968-H49H-B) on SA Biosensor, can bind Recombinant Human R-Spondin 1 / RSPO1 Protein, His Tag (Cat. No. 11083-H08H) with an affinity constant of 4.25 nM as determined in BLI assay (Sartorius Octet RED384) (QC tested) . 3.Loaded Recombinant Human LRP-6 Protein, His & AVI Tag, Avi-tag Biotinylated (Cat. No. 11968-H49H-B) on SA Biosensor, can bind Recombinant Human SOST/Sclerostin Protein, His Tag (Cat. No. 10593-H07H) with an affinity constant of 39.5 nM as determined in BLI assay (Sartorius Octet RED384) (Routinely tested) . 4.Loaded Recombinant Human LRP-6 Protein, His & AVI Tag, Avi-tag Biotinylated (Cat. No. 11968-H49H-B) on SA Biosensor, can bind Recombinant Human DKK-1 Protein, hFc Tag (Cat. No. 10170-H02H) with an affinity constant of 54.3 nM as determined in BLI assay (Sartorius Octet RED384) (Routinely tested) .

Met1-Pro630

The recombinant Human LRP6 consists of 637 amino acids and predicts a molecular mass of 72.22 kDa. It migrates as an approximately 79.8 kDa band in SDS-PAGE under reducing conditions.

Human