LRRC15, Cynomolgus/Rhesus makak (HEK293, Fc)

LRRC15 is a cell membrane-expressed protein belonging to the LRR superfamily. Involved in cell-cell and cell-ECM interactions. The LRRC15 protein regulates the infectivity of SARS-CoV-2 by interacting with its spike protein. LRRC15 activates the β1-integrin /FAK signaling pathway to promote ovarian cancer metastasis. LRRC15 Protein, Cynomolgus/Rhesus macaque (HEK293, Fc) is the recombinant cynomolgus-derived LRRC15 protein, expressed by heterologous system, with C-hFc labeled tag.

LRRC15 Protein, Cynomolgus/Rhesus macaque (HEK293, Fc), Rhesus Macaque; Cynomolgus, HEK293

12352202

102144360/707574 (Gene_ID) A0A2K5UKB6/F7FSB9 (Y22-G538) (Accession)

Approximately 90-100 kDa, based on SDS-PAGE under reducing conditions, due to the glycosylation.

[1]Ray U, et al. Exploiting LRRC15 as a Novel Therapeutic Target in Cancer. Cancer Res. 2022 May 3;82 (9) :1675-1681.|[2]Berkowitz RL, et al. The Elusive Coreceptors for the SARS-CoV-2 Spike Protein. Viruses. 2022 Dec 25;15 (1) :67.|[3]Ray U, et al. Targeting LRRC15 Inhibits Metastatic Dissemination of Ovarian Cancer. Cancer Res. 2022 Mar 15;82 (6) :1038-1054.

Room temperature in continental US; may vary elsewhere.

Recombinant Proteins