LRRC26 Antilichaam

The LRRC26 protein was initially identified as a cytokeratin-associated protein whose expression was elevated in multiple cancer cell lines and cancer specimens as well in normal prostate and salivary gland tissues (1) . LRRC26 was later found to negatively regulate the NF-kappaB activation and suppresses tumor growth and metastasis (2) . LRRC26 can also act to selectively alter the efficacy of large conductance calcium-activated K (BK) channels (3) .

389816

Q2I0M4

NP_001013675

Human

Unconjugated

Primary Antibodies

Cancer, Cell Cycle

LRRC26 antibody is affinity chromatography purified via peptide column.

Cat. No. 1312 - Human Prostate Tissue Lysate

1 mg/mL

LRRC26 antibody is supplied in PBS containing 0.02% sodium azide.

None

Blue Ice

LRRC26 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year.

IgG

LRRC26 antibody is human specific.

LRRC26

Cat. No. 1205 - Jurkat Cell Lysate

Leucine rich repeat containing 26

Homo sapiens

Egland KA, Liu XF, Squires S, et al. High expression of a cytokeratin-associated protein in many cancers. Proc. Natl. Acad. Sci. USA 2006; 103:5929-34.

Liu XF, Xiang L, Zhang Y, et al. CAPC negatively regulates NF-?B activation and suppresses tumor growth and metastasis. Oncogene 2012; 31:1673-82.

Almassy J and Begenisich T. The LRRC26 protein selectively alters the efficacy of BK channel activators. Mol. Pharmacol. 2012; 81:21-30.

LRRC26 Antibody: CAPC, bA350O14.10, CAPC, Leucine-rich repeat-containing protein 26, BK channel auxiliary gamma subunit LRRC26

ELISA, WB, IHC-P, IF

61966761

Liquid