Lrwd1 Antilichaam

The protein encoded by this gene interacts with components of the origin recognition complex (ORC) and regulates the formation of the prereplicative complex. The encoded protein stabilizes the ORC and therefore aids in DNA replication. This protein is required for the G1/S phase transition of the cell cycle. In addition, the encoded protein binds to trimethylated histone H3 in heterochromatin and recruits the ORC and lysine methyltransferases, which help maintain the repressive heterochromatic state. Two transcript variants encoding different isoforms have been found for this gene.

222229

Q9UFC0

Human, Mouse, Rat

A synthetic peptide corresponding to a sequence within amino acids 250-350 of human Lrwd1 (NP_690852.1) .

Unconjugated

Primary Antibodies

Cell Cycle

Affinity purification

U-87MG

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 65kDa

IgG

WB: 1:200 - 1:2000

Lrwd1

HeLa

HepG2

Jurkat

Mouse testis

Mouse thymus

Leucine rich repeats and WD repeat domain containing 1

Homo sapiens

CENP-33, ORCA, leucine-rich repeat and WD repeat-containing protein 1, ORC-associated protein, centromere protein 33, origin recognition complex-associated protein, testicular tissue protein Li 4

WB

Liquid