LSD1AOF2 Antilichaam [1B2F2 / 1B2E5]

The amine oxidase domain 2 (AOF2) gene encodes a nuclear protein (LSD1, ~95 kDa) containing a Swirm domain, a FAD-binding motif, and an amine oxidase domain. This protein is a component of several histone deacetylase complexes, though it silences genes by functioning as a histone demethylase. LSD1 is a chromatin-modifying enzyme, which serve as a docking module for the stabilization of the associated corepressor complex (es) on chromatin.

23028

O60341

O60341

Human

Ni-NTA purified truncated recombinant human LSD1 expressed in E. Coli strain BL21 (DE3) .

1B2F2 / 1B2E5

Unconjugated

Primary Antibodies

Other

Batch dependent

Ascitic fluid containing 0.03% sodium azide.

None

Blue Ice

LSD1/AOF2 monoclonal antibody can be stored at -20˚ C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

IgG1

KDM1A

Lysine (K) -specific demethylase 1A

Homo sapiens

Shi YJ, et.al Mol Cell. 2005 Sep 16;19 (6) :857-64.

Metzger E, et.al Nature. 2005 Sep 15;437 (7057) :436-9.

AOF2, KDM1, KIAA0601, LSD1, BRAF35-HDAC complex protein BHC110AOF2, BHC110

ELISA, WB, IHC

51315808