Luminespib (NVP-AUY922)
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
747412-49-3
AUY-922, VER-52296
C07489-5mg
HSP (HSP90)
Cytoskeletal Signaling
CCNC (=O) C1=NOC (=C1C2=CC=C (C=C2) CN3CCOCC3) C4=CC (=C (C=C4O) O) C (C) C
C26H31N3O5
Luminespib (AUY-922, NVP-AUY922, VER-52296) is a highly potent HSP90 inhibitor for HSP90α/β with IC50 of 13 nM /21 nM in cell-free assays, weaker potency against the HSP90 family members GRP94 and TRAP-1, exhibits the tightest binding of any small-molecule HSP90 ligand. Luminespib (AUY-922, NVP-AUY922) effectively downregulates and destabilizes the IGF-1Rβ protein and results in growth inhibition, autophagy and apoptosis. Phase 2.
2 years -80 in solvent
Beschrijving
Luminespib (NVP-AUY922) Beschikbaar in 5 mg. Wordt geleverd met droogijs. Bestel eenvoudig online met snelle levering.
Specificaties
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MS Solution sufficient for 400 Mini, 142 Midi, 33 Maxi
MS10
Each
MS pipette, variable vol µme 10~100 µL
MSP-100
1 Unit
MS 12-ch pipette, variable vol µme 20~200 µL
MSP-12X200
1 Unit
MS 12-ch pipette, variable vol µme 2~20 µL
MSP-12X20
1 Unit
MS Rocking anti-moistured shaker with 30 x 30 cm platform and flat non-slip rubber mat
MS-NRK-3001
1 Unit
MS Orbital Shaker with 30 x 30 cm platform and flat non-slip rubber mat
MS-NOR-30
1 Unit
MS Reciprocal anti-moistured shaker with 30 x 30 cm platform and flat non-slip rubber mat
MS-NRC-3001
1 Unit
MS pipette, variable vol µme 1000~10000 µL
MSP-10000
1 Unit