Lupartumab Amadotin
Gecertificeerd

Lupartumab Amadotin

Catalog #: HY-P99719-01
Maat: 1 mg
Droogijs Vereist

Kwaliteit

ISO Gecertificeerd

Levering

24-48 uur

Prijs -1%
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BTW niet inbegrepen
Gratis verzending vanaf €100

Technische Specificaties

Description

Lupartumab Amadotin (BAY 1129980) is an antibody–drug conjugate (ADC) consisting of a fully human C4.4A (LYPD3) -targeting mAb (BAY 1135626) conjugated to a novel, highly potent derivative of the microtubule-disrupting cytotoxic drug auristatin via a noncleavable alkyl hydrazide linker. Lupartumab Amadotin can be used for the research of non-small cell lung cancer[1].

CAS Number

1640972-00-4

Product Name Alternative

BAY 1129980; Anti-C4.4a antibody-drug conjugates

UNSPSC

12352203

Target

Antibody-Drug Conjugates (ADCs)

Related Pathways

Antibody-drug Conjugate/ADC Related

Applications

Cancer-programmed cell death

Field of Research

Cancer

Purity

99.61

Solubility

H2O

Smiles

[LupartumabAmadotin]

References & Citations

[1]Willuda J, et al. Preclinical Antitumor Efficacy of BAY 1129980-a Novel Auristatin-Based Anti-C4.4A (LYPD3) Antibody-Drug Conjugate for the Treatment of Non-Small Cell Lung Cancer. Mol Cancer Ther. 2017 May;16 (5) :893-904.

Shipping Conditions

Dry Ice

Storage Conditions

-80°C, protect from light

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-P99719/Lupartumab-Amadotin-SDS-MedChemExpress.pdf

Scientific Category

ADC Related

Clinical Information

No Development Reported

Beschrijving

Lupartumab Amadotin (BAY 1129980) is an antibody–drug conjugate (ADC) consisting of a fully human C4.4A (LYPD3) -targeting mAb (BAY 1135626) conjugated to a nov

Specificaties

ProductnaamLupartumab Amadotin
Categorie
Beschikbare grootte1 mg
CatalogusnummerHY-P99719-01