Ly-49F Antilichaam [HBF-719]

The monoclonal antibody HBF-719 reacts with the B6 allele of Ly49F, a member of the lectin-like homodimeric Ly49 family of cell surface receptors. Mouse Ly49 receptors exhibit allelic specificity for MHC class I Ia molecules and are thought to serve to prevent natural killer (NK) cells from attacking normal cells while allowing them to attack infected or transformed cells in which class I molecules have been downregulated. These inhibitory receptors are also expressed on subpopulations of mouse CD8+ T cells. The HBF-719 antibody stains ~11% of NK1.1+CD3- splenocytes, and 3.5% (2.5 month old) to 10.0% (11 month old) of CD8+ spleen cells from C57BL/6 mice.

16637

Q60653

Q60653

Mouse

CHO-K1 cells transfected with B6 allele of Ly49F gene

[HBF-719]

Unconjugated

Primary Antibodies

Immunology

0.5 mg/mL

Supplied in borate buffered saline, pH 8.2; No preservatives or amine-containing buffer salts added

None

Blue Ice

Store vial at 2-8˚ C

IgG1

Ly-49F

Ly-49F Antibody [HBF-719] for use in flow cytometry assays.

Klra6

Killer cell lectin-like receptor, subfamily A, member 6

Mus musculus

Ly-49

Flow

Liquid