LY2603618
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
LY2603618 is a potent (IC50 = 7nM) and selective (>1000x over Chk2) Checkpoint kinase 1 (Chk1) inhibitor.1 Chk1 is an important regulator of the DNA damage response – combination treatment of LY2603618 with other chemotherapeutic agents significantly increased tumor growth inhibition when compared to chemotherapeutic alone.2,3,4 LY2603618 caused a dramatic suppression of cell growth in MCF-7 and MDA-MB-231 human breast cancer cells via Chk1 inhibition induced upregulation of replication stress caused by oncogenes.5
Unconjugated
Off-white solid
-20°C
Beschrijving
LY2603618 Beschikbaar in 5 mg. Bestel eenvoudig online met snelle levering.
Specificaties
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