Lymfotactine

Lymphotactin is the only known member of the C-chemokine family and signals through the receptor XCR1, formally known as GPR5. The spleen shows the highest level of lymphotactin compared to peripheral leukocytes, lung, colon and small intestine. Lymphotactin is chemotactic towards lymphocytes but not towards monocytes or neutrophils. Recombinant human Lymphotactin is a 10.0 kDa protein consisting of 92 amino acid residues.

XCL1; LTN; ATAC; LPTN; SCM1; SCM-1; SCM1A; SCYC1; SCM-1a

6375

P47992

NP_002986.1

NM_002995

1q23

Human

Mouse, Human, Hamster, Bacteria

GSEVSDKRTC VSLTTQRLPV SRIKTYTITE GSLRAVIFIT KRGLKVCADP QATWVRDVVR SMDRKSNTRN NMIQTKPTGT QQSTNTAVTL TG

< 0.1 ng/µg of protein (< 1EU/µg)

> 98% by SDS-PAGE & HPLC analyses

Determined by its ability to chemoattract human T cells using a concentration of 10.0-100.0 ng/ml.

92

Lyophilized

10 kDa

E. coli