M-APTA
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
M-APTA (5'-S- (3-aminophenyl) -5'-thioadenosine) is a selective chemoprotective agent targeting methylthioadenosine phosphorylase (MTAP) . m-APTA can be converted into adenine, which is a crucial step in protecting normal cells from the toxicity of nucleobase analogues (NBA) . m-APTA is promising for research of MTAP-deficient cancers[1].
86072-47-1
5′-S- (3-Aminophenyl) -5′-thioadenosine
12352005
H302, H315, H319, H335
Phosphorylase
Metabolic Enzyme/Protease
Cancer
99.54
DMSO : 100 mg/mL (ultrasonic)
NC1=CC=CC(SC[C@@H]2[C@@H](O)[C@@H](O)[C@H](N3C=NC(C3=NC=N4)=C4N)O2)=C1
C16H18N6O3S
374.42
H302, H315, H319, H335
[1]Zhang S, et al. 5'-S- (3-aminophenyl) -5'-thioadenosine, a novel chemoprotective agent for reducing toxic side effects of fluorouracil in treatment of MTAP-deficient cancers. Mol Cancer Ther. 2025 Mar 10.
Blue Ice
-20°C, 3 years (Powder)
http://file.medchemexpress.com/batch_PDF/HY-W750643/m-APTA-SDS-MedChemExpress.pdf
Reference compound1
No Development Reported
Beschrijving
M-APTA (5'-S- (3-aminophenyl) -5'-thioadenosine) is a selective chemoprotective agent targeting methylthioadenosine phosphorylase (MTAP) . m-APTA can be convert
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