M-CSF Antilichaam

Macrophage CSF, also known as CSF1, is produced by monocytes, fibroblasts and endothelial cells. It stimulates the formation of macrophage colonies, enhances antibody-dependent, cell-mediated cytotoxicity by monocytes and macrophages, and inhibits bone resorption by osetoclasts. Natural human MCSF is a dimeric glycoprotein of 70-90 kD molecular weight, existing in multiple glycosylation forms. It binds to a 165 kD glycoprotein of the receptor tyrosine kinase subclass III, a family that includes the receptors for platelet derived growth factor (PDGF) and stem cell factor (SCF) .

1435

P09603

P09603

Human

Produced from sera of rabbits pre-immunized with highly pure (>98%) recombinant hM-CSF (human M-CSF) .

Unconjugated

Primary Antibodies, Functional Antibodies, Antibody Pairs

Growth Factors

Anti-hM-CSF specific antibody was purified by affinity chromatography employing immobilized hM-CSF matrix.

Batch dependent

None

Room Temp

M-CSF antibody is stable for at least 2 years from date of receipt at -20˚ C. The reconstituted antibody is stable for at least two weeks at 2-8˚ C. Frozen aliquots are stable for at least 6 months when stored at -20˚ C. Avoid repeated freeze-thaw cycles.

CSF1

Colony stimulating factor 1 (macrophage)

Homo sapiens

MCSF, CSF-1Macrophage colony-stimulating factor 1, Lanimostim, CSF-1

ELISA, WB, Neutralization Assay

311033367

Lyophilized