M2912
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
1460286-21-8
MSC2504877
C01460-5mg
PARP
DNA Damage/DNA Repair
CC1=CC=C2[N]1C=C (NC2=O) C3=CC=C (C=C3) C (C) (C) O
M2912 (MSC2504877) is a very potent TNKS1/TNKS2 inhibitor (IC50=0.6 nM for TNKS1) with exquisite selectivity over other PARP family enzymes and favorable compound properties. This inhibitor potently modulates the Wnt/β-catenin pathway by elevating the levels of axin2 (EC50=17 nM) and tankyrase in DLD1 cells in a dose-dependent manner resulting in reduced cellular Wnt reporter activity.
3 years -20°C powder
Beschrijving
M2912 Beschikbaar in 5 mg. Bestel eenvoudig online met snelle levering.
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