M6PR Antilichaam

Chicken polyclonal IgY Antibodies against cation-dependent mannose-6-phosphate receptor. This protein is a receptor for mannose-6-phosphate groups on lysosomal enzymes. The receptor forms a homodimer or homotetramer for intracellular targeting of lysosomal enzymes and export of newly synthesized lysosomal enzymes into the cell secretions. The receptor is an integral membrane protein that localizes to the trans-Golgi reticulum, endosomes, and the plasma membrane.

4074

P20645

NP_002346.1

Human, Mouse, Rat

60-114

Unconjugated

Primary Antibodies

Signal Transduction

Antigen affinity-purified

1 mg/mL

Phosphate-Buffered Saline. No preservatives added.

None

Blue Ice

M6PR antibody can be stored at 4˚ C for short term (weeks) . Long term storage should be at -20˚ C. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

31 kDa (calculated)

M6PR antibody can be used for the detection of M6PR by ICC, may also work for IHC.

M6PR

Mannose-6-phosphate receptor (cation dependent)

Homo sapiens

Klumperman, J. et al. Differences in the endosomal distributions of the two mannose 6-phosphate receptors J. Cell Biol. 121 (5), 997-1010 (1993)

MPR46, MPRD, Cation-dependent mannose-6-phosphate receptor, 46 kDa mannose 6-phosphate receptor, CD Man-6-P receptor, SMPR, MPR46, CD-MPR, MPR 46, MPR-46

ICC

4505061

Liquid