
...-MA1
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
ABX-MA1 is a humanized IgG2 monoclonal antibody inhibitor targeting MCAM/MUC18. ABX-MA1 significantly decreases homotypic aggregation and heterotypic adhesion to HUVECs, and the formation of experimental lung metastasis. ABX-MA1 potently inhibits tumor growth, angiogenesis, and MMP-2 expression in A375SM/WM2664 xenograft mice model, promising for melanoma research[1].
561063-60-3
12352203
MMP
Metabolic Enzyme/Protease
Cancer-Kinase/protease
Cancer
[1]Braeuer RR, et al. Transcriptional control of melanoma metastasis: the importance of the tumor microenvironment. Semin Cancer Biol. 2011 Apr;21 (2) :83-8.
Room temperature
http://file.medchemexpress.com/batch_PDF/HY-P991609/
Inhibitory Antibodies
No Development Reported
MMP-2
Beschrijving
ABX-MA1 is a humanized IgG2 monoclonal antibody inhibitor targeting MCAM/MUC18. ABX-MA1 significantly decreases homotypic aggregation and heterotypic adhesion t
Specificaties
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