...-MA1
Gecertificeerd

...-MA1

Catalog #: HY-P991609
Maat: 1 Each

Kwaliteit

ISO Gecertificeerd

Levering

24-48 uur

Prijs -1%
Login voor prijs
BTW niet inbegrepen
Gratis verzending vanaf €100

Technische Specificaties

Description

ABX-MA1 is a humanized IgG2 monoclonal antibody inhibitor targeting MCAM/MUC18. ABX-MA1 significantly decreases homotypic aggregation and heterotypic adhesion to HUVECs, and the formation of experimental lung metastasis. ABX-MA1 potently inhibits tumor growth, angiogenesis, and MMP-2 expression in A375SM/WM2664 xenograft mice model, promising for melanoma research[1].

CAS Number

561063-60-3

UNSPSC

12352203

Target

MMP

Related Pathways

Metabolic Enzyme/Protease

Applications

Cancer-Kinase/protease

Field of Research

Cancer

References & Citations

[1]Braeuer RR, et al. Transcriptional control of melanoma metastasis: the importance of the tumor microenvironment. Semin Cancer Biol. 2011 Apr;21 (2) :83-8.

Shipping Conditions

Room temperature

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-P991609/

Scientific Category

Inhibitory Antibodies

Clinical Information

No Development Reported

Isoform

MMP-2

Beschrijving

ABX-MA1 is a humanized IgG2 monoclonal antibody inhibitor targeting MCAM/MUC18. ABX-MA1 significantly decreases homotypic aggregation and heterotypic adhesion t

Specificaties

Productnaam...-MA1
Categorie
Beschikbare grootte1 Each
CatalogusnummerHY-P991609