MAb604.107
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
MAb604.107 is a human monoclonal antibody (mAb) targeting NOTCH1. MAb604.107 inhibits the proliferation and CD34/CD44 expression of primary T-ALL cells. MAb604.107 has anti-tumor activity in four tumor xenograft mouse models: MDA-MB-231, HCC-1806, BT-474, and HCT-116. MAb604.107 can be used in T acute lymphoblastic leukemia research[1].
12352203
Notch
Neuronal Signaling; Stem Cell/Wnt
Cancer-programmed cell death
Cancer
[MAb604.107]
[1]Sharma A, et al. A novel Monoclonal Antibody against Notch1 Targets Leukemia-associated Mutant Notch1 and Depletes Therapy Resistant Cancer Stem Cells in Solid Tumors. Sci Rep. 2015 Jun 5;5:11012.
Room temperature
http://file.medchemexpress.com/batch_PDF/HY-P991328/
Inhibitory Antibodies
No Development Reported
Beschrijving
MAb604.107 is a human monoclonal antibody (mAb) targeting NOTCH1. MAb604.107 inhibits the proliferation and CD34/CD44 expression of primary T-ALL cells. MAb604.
Specificaties
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