MAC-5576
Gecertificeerd

MAC-5576

Catalog #: HY-44484
Maat: 1 Each

Kwaliteit

ISO Gecertificeerd

Levering

24-48 uur

Prijs -1%
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Gratis verzending vanaf €100

Technische Specificaties

Description

MAC-5576 is a SARS-CoV-2 3CL protease inhibitor, with an IC50 of 81 nM. MAC-5576 also inhibits 3CLpro (IC50=0.5 μM), HAV 3Cpro (IC50=0.5 μM), and thrombin (IC50=13 μM) [1][2].

CAS Number

219929-01-8

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

SARS-CoV

Related Pathways

Anti-infection

Applications

COVID-19-anti-virus

Field of Research

Infection

Smiles

O=C(C1=CC=CS1)OC2=CC(Cl)=CN=C2

Molecular Formula

C10H6ClNO2S

Molecular Weight

239.68

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]Jan E Blanchard, et al. High-throughput screening identifies inhibitors of the SARS coronavirus main proteinase. Chem Biol. 2004 Oct;11 (10) :1445-53.|[2]Sho Iketani, et al. Lead compounds for the development of SARS-CoV-2 3CL protease inhibitors. Nat Commun. 2021 Apr 1;12 (1) :2016.

Shipping Conditions

Room temperature

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-44484/

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Beschrijving

MAC-5576 is a SARS-CoV-2 3CL protease inhibitor, with an IC50 of 81 nM. MAC-5576 also inhibits 3CLpro (IC50=0.5 μM), HAV 3Cpro (IC50=0.5 μM), and thrombin (IC50

Specificaties

ProductnaamMAC-5576
Categorie
Beschikbare grootte1 Each
CatalogusnummerHY-44484