MACTIDE-V
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
Epigenetic Reader Domain, YAP
Stem Cells, Chromatin/Epigenetic
MACTIDE-V is an orally active and selective peptide-drug conjugate targeting CD206. This compound delivers Verteporfin to CD206+ tumor-associated macrophages (TAM), thereby inhibiting the YAP/TAZ signaling pathway. It facilitates YAP exclusion from the nucleus, induces TAM polarization toward an anti-tumor phenotype, enhances phagocytosis and antigen presentation, and promotes T cell infiltration and NK cell activity. MACTIDE-V suppresses primary tumor growth and lung metastasis in triple-negative breast cancer (TNBC) mouse models.
C109H156N22O27S2
Ice Packs
-20°C
Beschrijving
MACTIDE-V Beschikbaar in 10 mg. Bestel eenvoudig online met snelle levering.
Specificaties
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