
Madindool A
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
Madindoline A is an IL-6 inhibitor. Madindoline A inhibits IL-6-dependent MH-60 cells and has no inhibitory effect on IL-6-independent MH-60 cells. In the presence of 0.1 U/mL IL-6, it inhibits IL-6-dependent MH-60 cells with an IC50 of 8 μM. Madindoline A has no antimicrobial effect[1].
184877-64-3
12352211
Interleukin Related
Immunology/Inflammation
Inflammation/Immunology
O[C@@](C1=CC=CC=C12)(CCO3)[C@@]3([H])N2C[C@]4(C(C(CCCC)=C(C4=O)C)=O)C
C22H27NO4
369.45
[1]Ramandeep Kaur, et al. Diversity-Oriented Synthetic Approaches for Furoindoline: A Review. Curr Org Synth. 2019;16 (3) :342-368.
Room temperature
http://file.medchemexpress.com/batch_PDF/HY-N14323/
Natural Products
No Development Reported
Beschrijving
Madindoline A is an IL-6 inhibitor. Madindoline A inhibits IL-6-dependent MH-60 cells and has no inhibitory effect on IL-6-independent MH-60 cells. In the prese
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