MAF Antibody - N-terminal regio : FITC (ARP38607_P050-FITC)

V-maf musculoaponeurotic fibrosarcoma oncogene homolog (avian)

CCA4, AYGRP, c-MAF, CTRCT21

4094

O75444

NP_001026974

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit, Zebrafish

The immunogen is a synthetic peptide directed towards the N terminal region of human MAF

MAF acts as a transcriptional activator or repressor. It is involved in embryonic lens fiber cell development. It recruits the transcriptional coactivators CREBBP and/or EP300 to crystallin promoters leading to up-regulation of crystallin gene during lens fiber cell differentiation. MAF is also involved in the initial chondrocyte terminal differentiation and the disappearance of hypertrophic chondrocytes during endochondral bone development. When overexpressed, MAF represses anti-oxidant reponse element (ARE) -mediated transcription. It may be involved either as an oncogene or as a tumor suppressor, depending on the cell context.

MAFB; FOSL1; MAF; FOS; ATF4; AHR; SUMO1; UBE2I; PML; SIN3A; HDAC2; SMARCA5; CEBPA; KDM5B; MAFA; SOX9; EP300; MAFG; USF2; CREBBP; MYB; JUN; ETS1; HOXD12

FITC: Fluorescein Isothiocyanate

Polyclonal Antibody

IHC, WB

Affinity Purified

0.5 mg/ml

Cow: 100%; Dog: 82%; Guinea Pig: 79%; Horse: 82%; Human: 100%; Mouse: 100%; Pig: 82%; Rabbit: 82%; Rat: 100%; Zebrafish: 93%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

38kDa

Gosmain, Y., (2007) J. Biol. Chem. 282 (48), 35024-35034

Wet Ice

373

MAF

MAF

Rabbit

Transcription factor Maf

NM_001031804

MASELAMSNSDLPTSPLAMEYVNDFDLMKFEVKKEPVETDRIISQCGRLI