MAGEL2 Antilichaam / MAGE-achtig eiwit 2

Prader-Willi syndrome (PWS) is caused by the loss of expression of imprinted genes in chromosome 15q11-q13 region. Affected individuals exhibit neonatal hypotonia, developmental delay, and childhood-onset obesity. Necdin (NDN), a gene involved in the terminal differentiation of neurons, localizes to this region of the genome and has been implicated as one of the genes responsible for the etiology of PWS. This gene is structurally similar to NDN, is also localized to the PWS chromosomal region, and is paternally imprinted, suggesting a possible role for it in PWS.

Western blot: 0.5-1 µg/mL, Immunohistochemistry (FFPE) : 2-5 µg/mL, Flow cytometry: 1-3ug/million cells, ELISA: 0.1-0.5 µg/mL

Q9UJ55

Human

An E.coli-derived human recombinant protein (amino acids Q578-A847) was used as the immunogen for the MAGEL2 antibody.

WB, IHC-P, FACS, ELISA

Antigen affinity purified

Antigen affinity purified

Lyophilized from 1X PBS with 2% Trehalose

This MAGEL2 antibody is available for research use only.

After reconstitution, the MAGEL2 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

0.5 mg/mL if reconstituted with 0.2ml sterile DI water

Optimal dilution of the MAGEL2 antibody should be determined by the researcher.

Cytoplasm, Nucleus

IHC staining of FFPE human liver cancer tissue with MAGEL2 antibody. HIER: boil tissue sections in pH8 EDTA for 20 min and allow to cool before testing.