Magnotriol B

Magnotriol B is a cholinesterase inhibitor with IC50 values of 12.63 nM and 14.5 nM against AChE and BChE, respectively. Magnotriol B also exhibits significant NO inhibitory activity with an IC50 of 2.02 μM. Magnotriol B can be used in the research of neurodegenerative and inflammatory diseases[1][2].

92829-71-5

12352005

Cholinesterase (ChE)

Neuronal Signaling

Inflammation/Immunology; Neurological Disease

OC1=CC=C(C(C2=CC(CC=C)=C(O)C=C2)=C1)O

C15H14O3

242.27

[1]Zhang B, et al. Four new honokiol derivatives from the stem bark of Magnolia officinalis and their anticholinesterase activities. Phytochemistry Letters, 2019, 29: 195-198.|[2]Nie W, et al. Biphenyl-type neolignans with NO inhibitory activity from the fruits of Magnolia tripetala. Phytochemistry Letters, 2021, 44: 222-226.

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-N15710/

Natural Products

No Development Reported

AChE; BChE