MAKK11 Antilichaam [4H66]

Mitogen-activated protein kinase 11.The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation, and development. This kinase is most closely related to p38 MAP kinase, both of which can be activated by proinflammatory cytokines and environmental stress. This kinase is activated through its phosphorylation by MAP kinase kinases (MKKs), preferably by MKK6. Transcription factor ATF2/CREB2 has been shown to be a substrate of this kinase.

5600

Q15759

NP_002742.3

Human

Purified truncated recombinant MAPK11 (aa251-363) -Trx fusion protein is expressed in E. Coli strain BL21 (DE3) .

4H6H6

Unconjugated

Primary Antibodies

Signal Transduction

Batch dependent

Ascitic fluid containing 0.03% sodium azide.

None

Blue Ice

MAPK11 monoclonal antibody can be stored at -20˚ C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

IgG1

MAPK11

Mitogen-activated protein kinase 11

Homo sapiens

Mol Cell Biol. 2005 Dec;25 (23) :10454-64.

Biol Reprod. 2005 Dec;73 (6) :1282-8. Epub 2005 Aug 24.

P38B, SAPK2, p38-2, PRKM11, SAPK2B, p38Beta, P38BETA2

ELISA, WB

20128774