MAKKAPK2 (fosfo Ser272) Antilichaam

This gene encodes a member of the Ser/Thr protein kinase family. This kinase is regulated through direct phosphorylation by p38 MAP kinase. In conjunction with p38 MAP kinase, this kinase is known to be involved in many cellular processes including stress and inflammatory responses, nuclear export, gene expression regulation and cell proliferation. Heat shock protein HSP27 was shown to be one of the substrates of this kinase in vivo. Two transcript variants encoding two different isoforms have been found for this gene.

9261

P49137

NP_116584.2

Human, Mouse, Rat

MAPKAPK2 (phospho Ser272) antibody was raised against a peptide sequence around phosphorylation site of Serine 272 (A-I-S (p) -P-G) derived from Human MAPKAPK2.

Unconjugated

Primary Antibodies

Phospho-Specific

Antibodies were purified by affinity-chromatography using epitope-specific peptide.

1 mg/mL

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Phospho-Specific

Blue Ice

Store antibody at -20˚ C for up to one year.

45 kDa

IgG

The antibody detects endogenous levels of MAPKAPK2 only when phosphorylated at serine 272.

Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100

MAPKAPK2

Mitogen-activated protein kinase-activated protein kinase 2

Homo sapiens

Zu Y.-L., Biochem. Biophys. Res. Commun. 200-1118-1124 (1994) .

The MGC Project Team; Genome Res. 14:2121-2127 (2004) .

Stokoe D., Biochem. J. 296:843-849 (1993) .

MAPK2; , MAPKAPK2, RPS6KC1

WB, IHC

32481209

Liquid