MAKKAPK3/MK3 Monoklonaal antilichaam
Gecertificeerd

MAKKAPK3/MK3 Monoklonaal antilichaam

Catalog #: AN200072P
Maat: 100 µL

Kwaliteit

ISO Gecertificeerd

Levering

24-48 uur

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Gratis verzending vanaf €100
Technische Documentatie

Technische Specificaties

Background

This gene encodes a member of the Ser/Thr protein kinase family. This kinase functions as a mitogen-activated protein kinase (MAP kinase) - activated protein kinase. MAP kinases are also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This kinase was shown to be activated by growth inducers and stress stimulation of cells. In vitro studies demonstrated that ERK, p38 MAP kinase and Jun N-terminal kinase were all able to phosphorylate and activate this kinase, which suggested the role of this kinase as an integrative element of signaling in both mitogen and stress responses. This kinase was reported to interact with, phosphorylate and repress the activity of E44, which is a basic helix-loop-helix transcription factor known to be involved in the regulation of tissue-specific gene expression and cell differentiation. Alternate splicing results in multiple transcript variants that encode the same protein.

Abbreviation

MAPKAPK3

UniProt

Q16644

Host

• Mouse

Reactivity

Human

Immunogen

Recombinant Human MAPKAPK3/MK3 Protein

Target

MDPT; MAPKAP; MAPKAP-K; MAPKAPK3;3PK; MAPKAP-K3; MAPKAP3; MAPKAPK-3; MDPT3; MK-3; anti MAPKAPK3; Chromosome 3p kinase; EC 2.7.11.1; MAP kinase-activated protein kinase 3; MAPK activated protein kinase 3; MAPK3; MAPK-activated protein kinase 3; MAPKAP kinase 3; MAPKAPK 3; MDPT326; Mitogen activated protein kinase activated protein kinase; Mitogen activated protein kinase activated protein kinase 3; mitogen-activated protein kinase-activated protein kinase 3

Clonality

• Monoclonal

Clone

4B6

Conjugation

Unconjugated

Applications

IHC-P

Field of Research

Signal Transduction

Purification

Protein A

Concentration

1 mg/mL

Dilution

IHC-P 1:50-1:200

Buffer

0.2 μm filtered solution in PBS

Shipping Conditions

Ice bag

Storage Conditions

This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.

Product MSDS

https://789.bio/eb/CSzXzY5K

Isotype

IgG2a

Beschrijving

MAKKAPK3/MK3 Monoklonaal antilichaam Beschikbaar in 100 µL. Bestel eenvoudig online met snelle levering.

Specificaties

ProductnaamMAKKAPK3/MK3 Monoklonaal antilichaam
Categorie
Beschikbare grootte100 µL
CatalogusnummerAN200072P