Mal-amide-PEG8-Val-Cit-PAB-OH
Gecertificeerd

Mal-amide-PEG8-Val-Cit-PAB-OH

Catalog #: TYD-01936-01
Maat: 10 mg

Kwaliteit

ISO Gecertificeerd

Levering

24-48 uur

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Gratis verzending vanaf €100
Technische Documentatie

Technische Specificaties

CAS Number

2387738-43-2

Target

ADC Linker

Related Pathways

Antibody-drug Conjugate/ADC Related

Bioactivity

Mal-amide-PEG8-Val-Cit-PAB-OH is a cleavable ADC linker, featuring a maleimide group, a hydrophilic PEG spacer, a Val-Cit dipeptide, and a PAB moiety. The maleimide group allows covalent bonding to free thiols on cysteine residues of proteins. The Val-Cit dipeptide is cleaved intracellularly by cathepsins to facilitate payload delivery via the PAB structure.

Smiles

N(C([C@@H](NC([C@@H](NC(CCOCCOCCOCCOCCOCCOCCOCCOCCNC(CCN1C(=O)C=CC1=O)=O)=O)[C@@H](C)C)=O)CCCNC(N)=O)=O)C2=CC=C(CO)C=C2

Molecular Formula

C44H71N7O16

Molecular Weight

954.072

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Beschrijving

Mal-amide-PEG8-Val-Cit-PAB-OH Beschikbaar in 10 mg. Bestel eenvoudig online met snelle levering.

Specificaties

ProductnaamMal-amide-PEG8-Val-Cit-PAB-OH
Categorie
Beschikbare grootte10 mg
CatalogusnummerTYD-01936-01