MAP1LC3A Antilichaam

Microtubule-associated proteins (MAPs) regulate microtubule stability and play critical roles in neuronal development and plasticity (1) . MAP1LC3A belongs to the MAP1 LC3 family of proteins that form mature complexes with MAP1A and MAP1B which are thought to be important in the formation and development of axons and dendrites (2) . MAP1LC3A is one of three isoforms of MAP1LC3, the mammalian homolog of yeast ATG8, an essential autophagy protein. These isoforms exhibit distinct expression patterns and MAP1LC3A, like MAP1LC3A but not MAP1LC3B, is post-translationally modified, suggesting the three isoforms may have different physiological functions (3) .

84557

Q9H492

NP_852610

Human

Unconjugated

Primary Antibodies

Autophagy

MAP1LC3A antibody is affinity chromatography purified via peptide column.

Cat. No. 1210 - HEK293 Cell Lysate

1 mg/mL

MAP1LC3A antibody is supplied in PBS containing 0.02% sodium azide.

None

Blue Ice

MAP1LC3A antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year.

IgG

MAP1LC3A antibody is human specific. At least two isoforms of MAP1LC3A are known to exist. MAP1LC3A antibody is predicted to not cross-react with MAP1LC3B or MAP1LC3C.

MAP1LC3A

Cat. No. 1201 - HeLa Cell Lysate

Cat. No. 10-301 - Human Brain Tissue Slide

Microtubule-associated protein 1 light chain 3 alpha

Homo sapiens

Mandelkow E and Mandelkow EM. Microtubules and microtubule-associated proteins. Curr. Opin. Cell Biol. 1995; 7:72-81.

Halpain S and Dehmelt L. The MAP1 family of microtubule-associated proteins. Genome Biol. 2006; 7:224.

He H, Dang Y, Dai F, et al. Post-translational modifications of three members of the human MAP1LC3 family and detection of a novel type of modification for MAP1LC3B. J. Biol. Chem. 2003; 278:29278-87.

MAP1LC3A Antibody: LC3, LC3A, ATG8E, MAP1ALC3, MAP1BLC3Autophagy-related protein LC3 A

ELISA, WB, IHC-P, IF

31563518

Liquid