MAP1LC3C Antilichaam

Microtubule-associated proteins (MAPs) regulate microtubule stability and play critical roles in neuronal development and plasticity (1) . MAP1LC3C belongs to the MAP1 LC3 family of proteins that form mature complexes with MAP1A and MAP1B which are thought to be important in the formation and development of axons and dendrites (2) . MAP1LC3C is one of three isoforms of MAP1LC3, the mammalian homolog of yeast ATG8, an essential autophagy protein. These isoforms exhibit distinct expression patterns and MAP1LC3C, like MAP1LC3A but not MAP1LC3B, is post-translationally modified, suggesting the three isoforms may have different physiological functions (3) .

440738

Q9BXW4

NP_001004343

Human

Unconjugated

Primary Antibodies

Autophagy

MAP1LC3C antibody is affinity chromatography purified via peptide column.

Cat. No. 1303 - Human Brain Tissue Lysate

1 mg/mL

MAP1LC3C antibody is supplied in PBS containing 0.02% sodium azide.

None

Blue Ice

MAP1LC3C antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year.

IgG

MAP1LC3C antibody is human, mouse and rat reactive. Multiple isoforms MAP1LC3C are known to exist. MAP1LC3C antibody is predicted to not cross-react with MAP1LC3A or MAP1LC3B.

MAP1LC3C

Cat. No. 10-301 - Human Brain Tissue Slide

Microtubule-associated protein 1 light chain 3 gamma

Homo sapiens

Mandelkow E and Mandelkow EM. Microtubules and microtubule-associated proteins. Curr. Opin. Cell Biol. 1995; 7:72-81.

Halpain S and Dehmelt L. The MAP1 family of microtubule-associated proteins. Genome Biol. 2006; 7:224.

He H, Dang Y, Dai F, et al. Post-translational modifications of three members of the human MAP1LC3 family and detection of a novel type of modification for MAP1LC3B. J. Biol. Chem. 2003; 278:29278-87.

MAP1LC3C Antibody: LC3C, ATG8JAutophagy-related protein LC3 C

ELISA, WB, IHC-P, IF

51972260

Liquid