MAP2K1 Antilichaam, KO gevalideerd

The protein encoded by this gene is a member of the dual specificity protein kinase family, which acts as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein kinase lies upstream of MAP kinases and stimulates the enzymatic activity of MAP kinases upon wide variety of extra- and intracellular signals. As an essential component of MAP kinase signal transduction pathway, this kinase is involved in many cellular processes such as proliferation, differentiation, transcription regulation and development.

5604

Q02750

Human, Mouse, Rat

A synthetic peptide corresponding to a sequence within amino acids 1-100 of human MAP2K1 (NP_002746.1) .

Unconjugated

Primary Antibodies

Antibody is Knockout validated.

Cell Cycle, Immunology, Neuroscience, Signal Transduction

Affinity purification

Jurkat

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 45kDa

IgG

MAP2K1

HeLa

A-431

MCF-7

Mouse Liver

Mouse Kidney

Mitogen-activated protein kinase kinase 1

Homo sapiens

Mitogen-activated protein kinase kinase 1, MAP2K1, MAPKK1, MEK1, MKK1, PRKMK1, CFC3, Mitogen-activated protein kinase kinase 2, MAP2K2, MAPKK2, MEK2, MKK2, PRKMK2, CFC

WB, IHC

Liquid