MAP3K1 (fosfo Th1402) Antilichaam

Component of a protein kinase signal transduction cascade. Activates the ERK and JNK kinase pathways by phosphorylation of MAP2K1 and MAP2K4. Activates CHUK and IKBKB, the central protein kinases of the NF-kappa-B pathway.

4214

Q13233

NP_005912.1

Human, Mouse, Rat

MAP3K1 (phospho Thr1402) antibody was raised against a peptide sequence around phosphorylation site of threonine 1402 (T-G-A (p) -G-F) derived from Human MAP3K1.

Unconjugated

Primary Antibodies

Phospho-Specific

Antibodies were purified by affinity-chromatography using epitope-specific peptide.

1 mg/mL

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Phospho-Specific

Blue Ice

Store antibody at -20˚ C for up to one year.

130 kDa

IgG

The antibody detects endogenous levels of MAP3K1 only when phosphorylated at threonine 1402.

Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100

MAP3K1

Mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase

Homo sapiens

Schmutz J., Nature 431:268-274 (2004) .

Xia Y., Genes Dev. 12:3369-3381 (1998) .

Vinik B.S., Mamm. Genome 6:782-783 (1995)

M3K1, MAP3K1, MAPKKK1, MEKK1

WB, IHC

153945765

Liquid