MAP4K2 Antilichaam - N-terminaal gebied: Biotine (ARP48631_P050-Biotine)

Mitogen-activated protein kinase kinase kinase kinase 2

GCK, BL44, RAB8IP

5871

Q12851

NP_004570

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Zebrafish

The immunogen is a synthetic peptide directed towards the N terminal region of human MAP4K2

MAP4K2 is a member of the serine/threonine protein kinase family. Although this kinase is found in many tissues, its expression in lymphoid follicles is restricted to the cells of germinal centre, where it may participate in B-cell differentiation. This kinase can be activated by TNF-alpha, and has been shown to specifically activate MAP kinases. This kinase is also found to interact with TNF receptor-associated factor 2 (TRAF2), which is involved in the activation of MAP3K1/MEKK1.The protein encoded by this gene is a member of the serine/threonine protein kinase family. Although this kinase is found in many tissues, its expression in lymphoid follicles is restricted to the cells of germinal centre, where it may participate in B-cell differentiation. This kinase can be activated by TNF-alpha, and has been shown to specifically activate MAP kinases. This kinase is also found to interact with TNF receptor-associated factor 2 (TRAF2), which is involved in the activation of MAP3K1/MEKK1.

HSP90AA1; UBC; MAP3K11; MAP3K1; POT1; MCM3AP-AS1; NACAD; SNRNP35; PRDX4; SERPINA4; HNRNPA2B1; XRCC6; DEFB1; TRAF2; RAB8A; MAP2K4

Biotin

Polyclonal Antibody

WB

Affinity Purified

0.5 mg/ml

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rat: 100%; Zebrafish: 86%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

91kDa

Wissing, J., (2007) Mol. Cell Proteomics 6 (3), 537-547

Wet Ice

820

MAP4K2

MAP4K2

Rabbit

Mitogen-activated protein kinase kinase kinase kinase 2

NM_004579

TVTSELAAVKIVKLDPGDDISSLQQEITILRECRHPNVVAYIGSYLRNDR