MAP4K4-IN-7
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
MAP4K4-IN-7 (Compound 8) is a MAP4K4 inhibitor. MAP4K4-IN-7 shows moderate inhibitory activity against TNIK, MAP4K4, and MINK1 with pIC50 values of 6.8, 6.8, and 6.7 respectively. MAP4K4-IN-7 can be used for the researches of cancer and neurological disease, such as schizophrenia[1].
1499162-60-5
12352005
H302-H315-H319-H335
MAP4K
MAPK/ERK Pathway
Cancer; Neurological Disease
FC1=NC=CC(C2=NC3=C(N)N=CN=C3C=C2)=C1
C12H8FN5
241.22
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
[1]Read J, et al. Tool inhibitors and assays to interrogate the biology of the TRAF2 and NCK interacting kinase. Bioorg Med Chem Lett. 2019 Aug 1;29 (15) :1962-1967.
Room temperature
http://file.medchemexpress.com/batch_PDF/HY-W402208/
Reference compound2
No Development Reported
MAP4K4/HGK; MAP4K6/MINK1; MAP4K7/TNIK
Beschrijving
MAP4K4-IN-7 (Compound 8) is a MAP4K4 inhibitor. MAP4K4-IN-7 shows moderate inhibitory activity against TNIK, MAP4K4, and MINK1 with pIC50 values of 6.8, 6.8, an
Specificaties
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