MAP4K5 Antilichaam - middengebied: Biotine (ARP33101_P050-Biotine)

Mitogen-activated protein kinase kinase kinase kinase 5

KHS, GCKR, KHS1, MAPKKKK5

11183

Q9Y4K4

NP_006566

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Yeast, Zebrafish

The immunogen is a synthetic peptide directed towards the middle region of human MAP4K5

MAP4K5 may play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway.This gene encodes a member of the serine/threonine protein kinase family, that is highly similar to yeast SPS1/STE20 kinase. Yeast SPS1/STE20 functions near the beginning of the MAP kinase signal cascades that is essential for yeast pheromone response. This kinase was shown to activate Jun kinase in mammalian cells, which suggested a role in stress response. Two alternatively spliced transcript variants encoding the same protein have been described for this gene.

CRK; ELAVL1; UBC; NEDD4; SETDB1; ZNF440; COPS5; HCK; GRB2; TANK; CRKL; TRAF2; ABL1; BCR

Biotin

Polyclonal Antibody

WB

Affinity Purified

0.5 mg/ml

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Yeast: 77%; Zebrafish: 86%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

95kDa

Wissing, J., (2007) Mol. Cell Proteomics 6 (3), 537-547

Wet Ice

846

MAP4K5

MAP4K5

Rabbit

Mitogen-activated protein kinase kinase kinase kinase 5

NM_006575

QGKSFKSDEVTQEISDETRVFRLLGSDRVVVLESRPTENPTAHSNLYILA