MAPI
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
MAPI is a polypeptide irreversible 3C cysteine protease (SV3CP) inhibitor. MAPI inhibits SV3CP by covalently binding its C-terminal Michael-acceptor extension to the active site thiol of SV3CP Cys 139. MAPI is promising for research of noroviruses infection[1].
1260620-30-1
12352209
Virus Protease
Anti-infection
Infection; Inflammation/Immunology
O=C(N[C@@H](CC1=CC=CC=C1)C(N[C@@H](CCC(N)=O)C(N[C@@H](CC(C)C)C(N[C@@H](CCC(N)=O)/C=C/C(OCC)=O)=O)=O)=O)[C@H](CCC(O)=O)NC(C)=O
C36H53N7O11
759.85
[1]Hussey RJ, et al. A structural study of norovirus 3C protease specificity: binding of a designed active site-directed peptide inhibitor. Biochemistry. 2011 Jan 18;50 (2) :240-9.
Room temperature
http://file.medchemexpress.com/batch_PDF/HY-P10828/
Peptides
Phase 2
Beschrijving
MAPI is a polypeptide irreversible 3C cysteine protease (SV3CP) inhibitor. MAPI inhibits SV3CP by covalently binding its C-terminal Michael-acceptor extension t
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