MAPK1 Antilichaam

Mitogen-activated protein kinase 1; extracellular signal-regulated kinase 2; protein tyrosine kinase ERK2; mitogen-activated protein kinase 2. This protein is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases. Upon activation, this kinase translocates to the nucleus of the stimulated cells, where it phosphorylates nuclear targets. Two alternatively spliced transcript variants encoding the same protein, but differing in the UTRs, have been reported for this gene.

5594

P28482

NP_620407.1

Human, Mouse, Rat

232-360

Unconjugated

Primary Antibodies

Signal Transduction, Cancer

Antigen affinity-purified

1 mg/mL

Phosphate-Buffered Saline. No preservatives added.

None

Blue Ice

MAPK1 antibody can be stored at 4˚ C for short term (weeks) . Long term storage should be at -20˚ C. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

41.3 kDa (calculated)

ERK2 antibody can be used for the detection of ERK2 by Western blot, may also work for IHC and ICC.

MAPK1

Mitogen-activated protein kinase 1

Homo sapiens

Bhalla, U. S., Ram, P. T., Iyengar, R. MAP kinase phosphatase as a locus of flexibility in a mitogen-activated protein kinase signaling network. Science 297: 1018-1023, 2002.

ERK2, PRKM1, PRKM2, Mitogen-activated protein kinase 1, ERT1, MAP kinase 1, ERK, p38, p40, p41, ERK2, ERK-2, MAPK2, P42MAPK, p41mapk, p42-MAPK

WB

20986531

Liquid