MAPK1 Antilichaam - C-terminalgebied: HRP (ARP58899 P050-HRP)

Mitogen-activated protein kinase 1

ERK, p38, p40, p41, ERK2, ERT1, NS13, ERK-2, MAPK2, PRKM1, PRKM2, P42MAPK, p41mapk, p42-MAPK

5594

P28482

NP_620407

Human, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Horse, Rabbit, Zebrafish

The immunogen is a synthetic peptide directed towards the C terminal region of human MAPK1

The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases. Upon activation, this kinase translocates to the nucleus of the stimulated cells, where it phosphorylates nuclear targets. Two alternatively spliced transcript variants encoding the same protein, but differing in the UTRs, have been reported for this gene.

Eif4ebp1; ATF2; RPS6KA3; RAF1; PTGDR; MAP2K6; MAP2K1; MAPK3; HDAC6; TP53; NEDD8; DGCR8; HMGB1; NAV1; PDCD6IP; CEP350; MAPK12; RPS6KA2; MAPK1; PDE4D; MBP; KRAS; SQSTM1; CUEDC2; GAB2; BRAF; RPS6KA1; MAP2K4; MAP2K2; ELK1; NOXA1; TIAL1; GADD45A; MAP3K10; SMAD

HRP: Horseradish Peroxidase

Polyclonal Antibody

WB

Affinity Purified

MAPK1 is strongly supported by BioGPS gene expression data to be expressed in Jurkat

0.5 mg/ml

Cow: 100%; Dog: 100%; Goat: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

41kDa

Wet Ice

360

MAPK1

MAPK1

Rabbit

Mitogen-activated protein kinase 1

NM_138957

PYLEQYYDPSDEPIAEAPFKFDMELDDLPKEKLKELIFEETARFQPGYRS