MAPK7 Antilichaam - middengebied HRP (ARP57731_P050-HRP)

Mitogen-activated protein kinase 7

BMK1, ERK4, ERK5, PRKM7

5598

Q13164

NP_620603

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

The immunogen is a synthetic peptide directed towards the middle region of human MAPK7

The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is specifically activated by mitogen-activated protein kinase kinase 5 (MAP2K5/MEK5) . It is involved in the downstream signaling processes of various receptor molecules including receptor type kinases, and G protein-coupled receptors. In response to extracelluar signals, this kinase translocates to cell nucleus, where it regulates gene expression by phosphorylating, and activating different transcription factors. Four alternatively spliced transcript variants of this gene encoding two distinct isoforms have been reported.

PRKCZ; NFE2L2; UBE2C; MAP3K2; TP53; MAP2K5; PML; DSG1; DSC1; PFDN6; VBP1; MAPK7; PFDN5; PFDN4; PFDN2; PFDN1; JUP; GAPDH; BAG3; PKM; LDHC; HSP90AB1; HSPA5; HSPA4; ATP5A1; ACTB; PPP3CA; TUBB; MYLK2; GANAB; CDC37; YWHAZ; YWHAH; YWHAG; YWHAE; UBC; HSP90B1; FS

HRP: Horseradish Peroxidase

Polyclonal Antibody

IHC, WB

Affinity Purified

0.5 mg/ml

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

88kDa

Wet Ice

816

MAPK7

MAPK7

Rabbit

Mitogen-activated protein kinase 7

NM_139034

FDMGVADGPQDGQADSASLSASLLADWLEGHGMNPADIESLQREIQMDSP