MARVELD1 Antilichaam

MARVELD1 Antibody: MARVELD1, (MARVEL domain-containing 1), is one of the MARVEL (MAL and related proteins for vesicle trafficking and membrane link) domain-containing proteins. It is a nuclear-localized protein that is widely expressed in normal human tissues. While it has been reported to be overexpressed in colon cancer, MARVELD1 protein levels are generally lower in several primary tumors including ovary, breast, kidney, bladder and liver. This lower level of MARVELD1 expression in tumors is thought to be due to a higher methylation status of the MARVELD1 promoter as treatment of MDA-MB-361 with 5-aza-2'-deoxycytidine restores MARVELD1 expression, suggesting that loss of MARVELD1 expression may contribute to tumorgenicity.

83742

Q9BSK0

EAW49903

Human, Mouse, Rat

Unconjugated

Primary Antibodies

Cancer

MARVELD1 Antibody is affinity chromatography purified via peptide column.

Cat. No. 1401 - Mouse Heart Tissue Lysate

1 mg/mL

MARVELD1 Antibody is supplied in PBS containing 0.02% sodium azide.

None

Blue Ice

MARVELD1 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

IgG

MARVELD1

MARVEL domain containing 1

Homo sapiens

Wang S, Li Y, Han F, et al. On of MARVELD1, a novel nuclear protein that is down-regulated in multiple cancers and silenced by DNA methylation. Cancer Lett.2009; 282:77-86.

Alves PM, Levy N, Stevenson BJ, et al. Identification of tumor-associated antigens by large scale analysis of genes expressed in human colorectal cancer. Cancer Immun.2008; 8:11.

Hatada I, Fukasawa M, and Kimura M. Genome-wide profiling of promoter methylation in human. Oncogene2006; 25:3059-64.

MARVELD1 Antibody: MRVLDC1, MARVEL domain-containing protein 1

ELISA, WB

119570288

Liquid