MASP2 Mouse Monoclonal Antibody [Kloon ID: LBI7C4]

This gene encodes a member of the peptidase S1 family of serine proteases. The encoded preproprotein is proteolytically processed to generate A and B chains that heterodimerize to form the mature protease. This protease cleaves complement components C2 and C4 in order to generate C3 convertase in the lectin pathway of the complement system. The encoded protease also plays a role in the coagulation cascade through cleavage of prothrombin to form thrombin. Myocardial infarction and acute stroke patients exhibit reduced serum concentrations of the encoded protein. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Feb 2016]

Carrier-free (BSA/glycerol-free) MASP2 mouse monoclonal antibody, clone LBI7C4

MAP-2; MAP19; MASP-2; MASP1P1; sMAP

Homo sapiens MBL associated serine protease 2 (MASP2), transcript variant 1, mRNA.

10747

O00187

Unconjugated

Complement and coagulation cascades

Complement and coagulation cascades

WB 1:500

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Druggable Genome, Protease, Secreted Protein

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

MASP2

https://www.ncbi.nlm.nih.gov/gene/?term=10747

https://www.uniprot.org/uniprot/O00187