Maspin (SerpinB5)
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
Maspin (mammary serine protease inhibitor) is a non-inhibitory serpin that is expressed predominantly in normal mammary epithelial cells but at significantly reduced levels or absent in most breast carcinomas. It has the ability to block the growth, invasiveness, and metastatic potential of breast and lung tumors. This anti-tumor activity is achieved, in part, by the ability of Maspin to inhibit angiogenesis and to preferentially promote apoptosis of tumor cells. Recombinant human Maspin is a 42.2 kDa non-glycosylated protein containing 375 amino acid residues.
SERPINB5; PI5; maspin
5268
P36952
NP_002630.2
NM_002639
18q21.3
Human
Human
MDALQLANSA FAVDLFKQLC EKEPLGNVLF SPICLSTSLS LAQVGAKGDT ANEIGQVLHF ENVKDIPFGF QTVTSDVNKL SSFYSLKLIK RLYVDKSLNL STEFISSTKR PYAKELETVD FKDKLEETKG QINNSIKDLT DGHFENILAD NSVNDQTKIL VVNAAYFVGK WMKKFPESET KECPFRLNKT DTKPVQMMNM EATFCMGNID SINCKIIELP FQNKHLSMFI LLPKDVEDES TGLEKIEKQL NSESLSQWTN PSTMANAKVK LSIPKFKVEK MIDPKACLEN LGLKHIFSED TSDFSGMSET KGVALSNVIH KVCLEITEDG GDSIEVPGAR ILQHKDELNA DHPFIYIIRH NKTRNIIFFG KFCSP
< 0.1 ng/µg of protein (< 1EU/µg)
> 97% by SDS-PAGE & HPLC analyses
Data not available.
375
Lyophilized
42.1 kDa
E. coli
Beschrijving
Maspin (mammary serine protease inhibitor) is a non-inhibitory serpin that is expressed predominantly in normal mammary epithelial cells but at significantly re
Specificaties
Recent bekeken producten
H&E Mount, Permanent Mountindg media for coverslipping H&E stains from water,
NB315
125 mL
SCD polyclonal antibody
GTR18043932-01
50 μL
(KO Validated) SUMO1 Polyclonal Antibody
E-AB-92410-01
60 µL
Salicylate hydroxylase, Microorganism
HY-E70520-01
1 KU
Purified Diphtheria Toxoid protein (cGMP/USP, vaccine grade, ~1500-2500 Lf/ml; Low endotoxin)
DTOX16-N-500
500 µg
BioCoupler® Glass Set (16 oz) x12
BCS1612
12 Each
BioCoupler® x 48
BC48
48 Each
BioTilt™ 25 (BT25)
BT25
25 Bundles
Recent gezochte producten
H&E Mount, Permanent Mountindg media for coverslipping H&E stains from water,
NB315-40
40 mL
Probe Mount, Permanent Mounting media for mounting and coverslipping of Special stains & Immunofluorescence and In-Situ Stains FROM WATER
NB316-30
30 mL
H&E Mount, Permanent Mountindg media for coverslipping H&E stains from water,
NB315
125 mL
Probe Mount, Permanent Mounting media for mounting and coverslipping of Special stains & Immunofluorescence & In-Situ Stains FROM WATER
NB316
60 mL
Holder for water tank for mounting
CHA4068
1 Each
Permount Mounting Medium
21750009-2
500 mL
Wall Mount for S1
TH9066-11
each
PROJECTION SCREEN, DELUXE Tripod Stand – foldable, metal stand, with four position vertical adjustment; for mounting of projection screens.
4022650/8
1 Each