Matairesinol-d6

Matairesinol-d6 is the deuterium labeled Matairesinol. Matairesinol confers anti-allergic effects in an allergic dermatitis mouse model. DfE-induced changes in IL-4 and IFN-γ mRNA expression in the ears of NC/Nga mice were reversed by matairesinol application[1].

1346600-02-9

12352005

Endogenous Metabolite; Isotope-Labeled Compounds

Metabolic Enzyme/Protease; Others

Infection

10 mM in DMSO

C([C@H]1[C@H](CC2=C(C(OC)=C(O)C(=C2[2H])[2H])[2H])C(=O)OC1)C3=C(C(OC)=C(O)C(=C3[2H])[2H])[2H]

C20H16D6O6

364.42

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216. |[2]Sung YY, Lee AY, Kim HK. Forsythia suspensa fruit extracts and the constituent matairesinol confer anti-allergic effects in an allergic dermatitis mouse model. J Ethnopharmacol. 2016;187:49-56.

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-N3312S/

Isotope-Labeled Compounds

No Development Reported