MBTPS1 Antilichaam

This gene encodes a member of the subtilisin-like proprotein convertase family, which includes proteases that process protein and peptide precursors trafficking through regulated or constitutive branches of the secretory pathway. The encoded protein undergoes an initial autocatalytic processing event in the ER to generate a heterodimer which exits the ER and sorts to the cis/medial-Golgi where a second autocatalytic event takes place and the catalytic activity is acquired. It encodes a type 1 membrane bound protease which is ubiquitously expressed and regulates cholesterol or lipid homeostasis via cleavage of substrates at non-basic residues. Mutations in this gene may be associated with lysosomal dysfunction.

8720

Q14703

Human, Mouse

Recombinant fusion protein containing a sequence corresponding to amino acids 803-1052 of human MBTPS1 (NP_003782.1) .

Unconjugated

Primary Antibodies

Cell Cycle, Signal Transduction

Affinity purification

K-562

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 117kDa

IgG

WB: 1:500 - 1:2000

MBTPS1

Mouse pancreas

Membrane bound transcription factor peptidase, site 1

Homo sapiens

PCSK8, S1P, SEDKF, SKI-1, membrane-bound transcription factor site-1 protease, endopeptidase S1P, proprotein convertase subtilisin/kexin type 8, site-1 protease, subtilisin/kexin isozyme-1

WB

Liquid