MBTPS2 Antilichaam: HRP (ARP47191 P050-HRP)

Membrane-bound transcription factor peptidase, site 2

S2P, IFAP, KFSD, OI19, KFSDX, OLMSX, BRESEK

51360

O43462

NP_056968

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

The immunogen is a synthetic peptide directed towards the following sequence LVVVVVGGWTVVYLTDLVLKSSVYFKHSYEDWLENNGLSISPFHIRWQTA

This gene encodes a intramembrane zinc metalloprotease, which is essential in development. This protease functions in the signal protein activation involved in sterol control of transcription and the ER stress response. Mutations in this gene have been associated with ichthyosis follicularis with atrichia and photophobia (IFAP syndrome) ; IFAP syndrome has been quantitatively linked to a reduction in cholesterol homeostasis and ER stress response.

UBC; ATF6B

HRP: Horseradish Peroxidase

Polyclonal Antibody

Affinity Purified

0.5 mg/ml

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

57 kDa

Wet Ice

519

MBTPS2

MBTPS2

Rabbit

Membrane-bound transcription factor site-2 protease

NM_015884

LVVVVVGGWTVVYLTDLVLKSSVYFKHSYEDWLENNGLSISPFHIRWQTA