MC-val-ala-nhs-ester
Gecertificeerd

MC-val-ala-nhs-ester

Catalog #: TYD-02069-01
Maat: 10 mg

Kwaliteit

ISO Gecertificeerd

Levering

24-48 uur

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Gratis verzending vanaf €100
Technische Documentatie

Technische Specificaties

CAS Number

1895916-22-9

Target

ADC Linker

Related Pathways

Antibody-drug Conjugate/ADC Related

Bioactivity

MC-Val-Ala-NHS ester is a cleavable ADC linker featuring maleimide and NHS ester groups. The Val-Ala linker is susceptible to cleavage by cathepsin B. The maleimide group can react with thiol groups, as can the MC component. The NHS ester reacts specifically and efficiently with amines (such as lysine residue side chains or aminosilane-coated surfaces) under neutral or mildly alkaline conditions, forming covalent bonds. Reagent grade, intended for research use only.

Smiles

O(C([C@@H](NC([C@@H](NC(CCCCCN1C(=O)C=CC1=O)=O)[C@@H](C)C)=O)C)=O)N2C(=O)CCC2=O

Molecular Formula

C22H30N4O8

Molecular Weight

478.496

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Beschrijving

MC-val-ala-nhs-ester Beschikbaar in 10 mg. Bestel eenvoudig online met snelle levering.

Specificaties

ProductnaamMC-val-ala-nhs-ester
Categorie
Beschikbare grootte10 mg
CatalogusnummerTYD-02069-01