McCC1 Antilichaam / 3-methylcrotonyl-CoA carboxylase 1

This gene encodes the large subunit of 3-methylcrotonyl-CoA carboxylase. This enzyme functions as a heterodimer and catalyzes the carboxylation of 3-methylcrotonyl-CoA to form 3-methylglutaconyl-CoA. Mutations in this gene are associated with 3-Methylcrotonylglycinuria, an autosomal recessive disorder of leucine catabolism.

Western blot: 0.5-1 µg/mL, Flow cytometry: 1-3ug/million cells, ELISA: 0.1-0.5 µg/mL

Q96RQ3

Human, Mouse, Rat

An E.coli-derived human recombinant protein (amino acids Q104-E715) was used as the immunogen for the MCCC1 antibody.

WB, FACS, ELISA

Antigen affinity purified

Antigen affinity purified

Lyophilized from 1X PBS with 2% Trehalose

This MCCC1 antibody is available for research use only.

After reconstitution, the MCCC1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

0.5 mg/mL if reconstituted with 0.2ml sterile DI water

Optimal dilution of the MCCC1 antibody should be determined by the researcher.

Cytoplasm

Western blot testing of 1) human SiHa, 2) human RT4 and 3) rat liver tissue lysate with MCCC1 antibody. Predicted molecular weight ~80 kDa.