McCC2 Antilichaam / Methylcrotonoyl-CoA carboxylase bètaketen

This gene encodes the small subunit of 3-methylcrotonyl-CoA carboxylase. This enzyme functions as a heterodimer and catalyzes the carboxylation of 3-methylcrotonyl-CoA to form 3-methylglutaconyl-CoA. Mutations in this gene are associated with 3-Methylcrotonylglycinuria, an autosomal recessive disorder of leucine catabolism. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Western blot: 0.5-1 µg/mL, Immunohistochemistry (FFPE) : 2-5 µg/mL, Flow cytometry: 1-3ug/million cells, ELISA: 0.1-0.5 µg/mL

Q9HCC0

Human, Mouse, Rat

An E.coli-derived human recombinant protein (amino acids R21-D330) was used as the immunogen for the MCCC2 antibody.

WB, IHC-P, FACS, ELISA

Antigen affinity purified

Antigen affinity purified

Lyophilized from 1X PBS with 2% Trehalose

This MCCC2 antibody is available for research use only.

After reconstitution, the MCCC2 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

0.5 mg/mL if reconstituted with 0.2ml sterile DI water

Optimal dilution of the MCCC2 antibody should be determined by the researcher.

Cytoplasm (Mitochondria)

IHC staining of FFPE human breast cancer tissue with MCCC2 antibody. HIER: boil tissue sections in pH8 EDTA for 20 min and allow to cool before testing.