McIZ (B. subtilis)

MciZ (B. subtilis), a 40-amino-acid peptide, inhibits the GTPase activity of FtsZ that prevents inappropriate Z-ring formation during sporulation[1].

12352209

Bacterial

Anti-infection

Infection

O=C([C@@H](N)CCSC)N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N1[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N2[C@H](C(O)=O)CCC2)=O)CCCCN)=O)CO)=O)[C@H](CC)C)=O)CC3=CNC4=CC=CC=C34)=O)CC(O)=O)=O)CCCCN)=O)C(C)C)=O)CC5=CC=C(O)C=C5)=O)CCC(N)=O)=O)CC6=CC=CC=C6)=O)[C@@H](C)O)=O)CCCNC(N)=N)=O)=O)CC7=CC=C(O)C=C7)=O)CCC(O)=O)=O)CCCCN)=O)CC(C)C)=O)CCCCN)=O)C)=O)CCCNC(N)=N)=O)[C@H](CC)C)=O)CCC(O)=O)=O)CC8=CNC9=CC=CC=C89)=O)C)=O)CCCCN)=O)=O)C(C)C)=O)CC(C)C)=O)C(C)C)=O)C(C)C)=O)=O)CCCCN)=O)CCC1)=O)CCSC)=O)CCCNC(N)=N)=O)CC%10=CNC=N%10)=O)C(C)C)=O)CCCCN

C222H355N61O52S2

4774.70

[1]Handler AA, et al. Peptide inhibitor of cytokinesis during sporulation in Bacillus subtilis. Mol Microbiol. 2008 May;68 (3) :588-99.

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-P10814/

Peptides

No Development Reported